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New research from ISB’s Gibbons Lab shows that computer models of gut metabolism can predict whether probiotics will successfully establish in an individual’s microbiome and how dietary prebiotics shape health-related molecules in the gut. The findings point toward a future of more personalized, predictable microbiome-based interventions.

Six leading experts from across the field presented new insights to more than 1,000 registrants worldwide, with over 400 participants joining live.

Researchers at ISB have developed personalized models to predict C. diff colonization risk and test targeted probiotics. This approach could prevent infection before it starts and paves the way for precision microbiome therapies tailored to individual gut ecosystems.

ISB scientists have developed a simple, low-cost method to measure the total amount of bacteria in the gut using existing sequencing data. This breakthrough could speed up microbiome research and unlock new insights into health and disease.

ISB’s Gibbons Lab developed a breakthrough method that analyzes food-derived DNA in fecal metagenomes, allowing for data-driven diet tracking without the need for burdensome questionnaires.

ISB has been selected as a winner of the 2024 Amazon Web Services (AWS) IMAGINE Grant. The grant will support ISB’s continued development of My Digital Gut, an online decision-support platform that will help make microbiome-informed nutrition and healthcare personalized, predictive, and preventive.