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Gibbons Lab Awarded NIH R01 to Explore Precision Nutrition

The ecological structure of the human gut microbiome helps determine nutritional and phenotypic responses to diet. However, a clear mapping does not yet exist between diet, gut microbial ecology, gut microbial community metabolism, and human metabolic phenotypes. This proposal, entitled “CyberGut: towards personalized human-microbiome metabolic modeling for precision health and nutrition“, provides five years of funding from the National Institutes of Health (NIH) for the design and testing of an…

Dr. Christian Diener, postdoc in ISB's Gibbons Lab.

New Modeling Tool Allows Microbiome Researchers to Map Community Ecology to Ecosystem Function

A promising new open-source metabolic modeling tool provides microbiome researchers a path forward in predicting ecosystem function from community structure. News of the software package, called MICOM, was developed in part by researchers in ISB’s Gibbons Lab, and its uses were published in the journal mSystems.

Using Blood to Predict Gut Microbiome Diversity

Predicting the alpha diversity of an individual’s gut microbiome is possible by examining metabolites in the blood. The robust relationship between host metabolome and gut microbiome diversity opens the door for a fast, cheap and reliable blood test to identify individuals with low gut diversity.

Alex Carr Joins the Lab

Alex Carr will join the Institute for Systems Biology for his PhD work, co-advised by Nitin Baliga and Sean Gibbons. Alex is a graduate student in the Molecular Engineering Program at the University of Washington. Prior to starting graduate school at UW, Alex worked in Adam Arkin’s lab at UC Berkeley, characterizing species-species interactions in synthetic gut bacterial communities. For his dissertation, Alex will pursue novel experimental and computational approaches…