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The 2021 ISB Virtual Microbiome Series highlighted recent advances toward understanding general patterns of commensal population genomic variation within the human gut, how fine-scale commensal genomic variation is influenced by host phenotypic variation, and whether or not commensal genomic variation has an impact on human health and disease.

We hosted the 2021 ISB Virtual Microbiome Series consisting of a two-day virtual course and a one-day symposium examining the latest cutting-edge microbiome research. 

This was the second microbiome series of its kind and was geared toward graduate students, postdocs, principal investigators, industry scientists, educators, clinicians, or any other variety of microbiome-curious people from across the globe. 

The event was recorded. You can watch the full playlist on YouTube, or scroll down to see the full collection of videos.

Series background

We are island ecosystems, rapidly colonized at birth by a diverse array of microorganisms. Many of these commensal microbial populations persist in and on our bodies for years, decades, perhaps as long as a century. For our microbes, these human timescales are equivalent to tens of thousands of generations, which is equivalent to hundreds of thousands or even millions of years of evolution in a vertebrate such as ourselves. While we are beginning to understand how disruptions to the ecological structure of commensal microbial communities can impact host health, less is known about how rapid evolutionary dynamics within individual commensal populations throughout a host’s lifespan can influence ecosystem function.

ISB hosted a series of events in October of 2021 that highlighted recent advances toward understanding general patterns of commensal population genomic variation within the human gut, how fine-scale commensal genomic variation is influenced by host phenotypic variation, and whether or not commensal genomic variation has an impact on human health and disease.

Virtual Microbiome Course – Day 1

Dr. Sean Gibbons delivers opening remarks.
Dr. Christian Diener: “Analyzing amplicon sequencing data with Qiime 2, part 1”
Dr. Christian Diener: “Analyzing amplicon sequencing data with Qiime 2, part 2”

Virtual Microbiome Course  – Day 2

Dr. Sean Gibbons delivers opening remarks.
Dr. Christian Diener: “Building metabolic models of bacterial isolates”
Dr. Christian Diener: “Reverse ecology: inferring environmental interactions with metabolic models”
Priyanka Baloni: “Connecting the dots: How our guy may influence the brain and lifespan”
Dr. Sean Gibbons delivers closing remarks.

Virtual Microbiome Symposium

Welcoming remarks by Dr. Sean Gibbons

Session 1 (Theory): Population genomics of commensal bacteria

Dr. Jesse Shapiro: “Does diversity beget diversity in the human gut microbiome?”
Dr. Benjamin Good: “Eco-evolutionary feedbacks in the gut microbiome”
Dr. Christian Diener moderates a panel discussion from session 1.

Session 2 (Natural History): Identifying signatures of within-host adaptation

Dr. Nandita Garud: “Evolutionary and ecological dynamics in the human gut microbiome from birth through adulthood”
Dr. Mathieu Groussin: “Evolution of host-microbiome systems in humans”
Dr. Tomasz Wilmanski moderates a panel discussion from session 2.

Session 3 (Clinical Relevance): Functional consequences of evolution in host-microbe systems

Dr. Tami Lieberman: “Tracking de novo mutations to understand microbial ecology on the skin”
Dr. Taichi Suzuki: “Codiversification of gut microbiota with humans”
Dr. Noa Rappaport moderates a panel discussion from session 3.
Dr. Sean Gibbons delivers closing remarks.

Watch the full playlist on YouTube.